Medicine net August 10 news of the country mourning!
A 6.6-magnitude earthquake shook the jinghe county of xinjiang province yesterday (9 a.m.) after a 7.0-magnitude earthquake hit jiuzhaigou, sichuan province, at 9 p.m. According to the current report, the casualties of jiuzhaigou in sichuan province have been relatively more severe with the loss of casualties.
After the wenchuan earthquake and the yushu earthquake in qinghai, the relevant state organs and people's attention to the earthquake has increased, and the response speed has been greatly improved.
After the earthquake, the most important job is to rescue the injured. In the rescue, besides medical personnel, a large number of emergency medicine, medical equipment and consumables are needed.
The following author only makes a general scan of the treatment drugs mainly involved in the treatment, for the reader's reference (the list of medicines is at the end of the article).
▍ anti-shock class of drugs
In the process of earthquake, heavy injury patients with shock, the most common one of the critical situation, will cause disorder in the body blood circulation, effective circulating blood volume decreased dramatically, microcirculation perfusion inadequacy, causing tissue ischemia hypoxia, metabolic disorders and important organ damage of acute cycle dysfunction syndrome.
It is often necessary to use vasoactive drugs and glucocorticoid drugs. At present, the market size of this class of drugs is relatively small, and the market size is expected to be within 5 billion yuan.
The drugs used in shock treatment include norepinephrine, epinephrine, and hydroxylamine.
When the patient's transfusion capacity is insufficient, the blood supply of vital organs to maintain blood pressure can be maintained. The use of amplifying, acid, cardiac and revascularization did not improve, but worsened, with a hydroxylamine or small dose of NE; It has been used to expand the blood vessel but blood pressure is still low or unstable, the veins are weak, and can be used with a hydroxylamine or small dose of NE.
There are also commonly used corticosteroid drugs, such as dexamethasone and methylprednisolone, in the anti-shock. This class of drugs mainly play a moderate endotoxin of cell damage, stabilize lysosomal membrane to reduce slow excitation peptide, shock caused by material such as histamine release, and promote lactic acid accumulation, converted to glycogen to prevent blocking a - receptor relieve the joint action of arteriole spasm, etc.
▍ hemostatic drugs
Hemostasis is one of the most common medicines for clinical first aid.
The coagulation mechanisms of hemostatic drugs include narrowing of the arteries and capillaries, enhancing platelet function, speeding up or strengthening the blood coagulation process, and inhibiting the dissolving of clots. On behalf of the drugs have a blood clotting enzyme, thrombin, prothrombin complex, freeze-dried blood coagulation factor Ⅷ, freeze-dried fibrinogen, vitamin K1, vitamin K3, vitamin K4 and diacetyl ethylenediamine acetate ammonia, etc.
Due to the post-earthquake trauma, there will be more use of external wound hemostasis drugs such as hemostatic sealants, gelatin sponges, absorptive hemostasis, yunnan baiyao, etc.
At present, the market of hemostatic medicine is more than 6 billion yuan. The representative manufacturers of these drugs include Beijing kangchen pharmaceutical, shandong penglaiconno pharmaceutical, fosun pharmaceutical co., inc., jinzhou auhong pharmaceutical co., etc.
▍ anti-infection drugs
At present, in China's pharmaceutical market, anti-infection-resistant drugs are still the largest market share, with market size exceeding 150 billion yuan and market share exceeding 15%. There are thousands of enterprises in our country that produce and sell these drugs.
Most of the injured in the earthquake are mainly trauma, and anti-infective treatment is also very important.
Most of the clinic is mainly cephalosporin and penicillin, such as ceftriaxone sodium, cefotaxime sodium, penicillin, amoxicillin, etc. It is also possible to use quinolones, such as levofloxacin, norfloxacin, and amitacin, according to the injured site and infection.
Domestic leading anti-infective drug production and sales enterprises such as Harbin pharmaceutical group, north China pharmaceutical, lu anti - medicine, shiyao group, federal pharmaceutical and so on.
▍ anesthesia and analgesic drugs
Patients who are relatively seriously injured after the earthquake will be involved in surgical treatment in the course of the treatment, which is bound to use anesthesia, especially local and analgesic drugs.
At present, domestic local anesthetic drug market is about 2 billion yuan. The commonly used local anesthetic varieties of amino acid esters (procaine, benzocaine), the amide class (lidocaine, cloth than paid), amino ethers and amine ketone (dyclonine), etc.
The domestic pharmaceutical market mainly includes astrazeneca, yangzijiang, jichuan pharmaceutical, chenxin pharmaceutical, qilu pharmaceutical and other production and sales.
▍ opioid analgesics
Opioid analgesics mainly include diazocine, codeine, bihydrocodeine, hydroxyketone, oxycodone, methadone, morphine, fentanyl, and pethidine.
At present, the market of opioid painkillers in China is more than 5 billion yuan, and the main production and sales manufacturers have yangzijiang, southwest pharmaceutical, people's pharmaceutical, hengrui medicine and so on.
▍ rehydration class of drugs
After an earthquake, more patients are crushed, and improper handling can turn into crush syndrome.
Crush and crush syndrome are two different stages of a disease. Crush injury is an injury that occurs after the body is crushed. The condition can be light and heavy. Crush syndrome is a series of complications, such as muscle necrosis, even heart failure and acute renal failure.
A large number of rapid intravenous fluids can play a vital role in improving patient crush injury and preventing the occurrence of limb crush syndrome.
In clinic, the tonic drugs mainly include sodium chloride injection, glucose injection, mannitol injection, hydroxyethyl starch injection, etc., and oral rehydration salts.
Despite several provinces of our country in recent years large infusion drugs taken various restrictions on the use of measures, but the overall market demand, consumption still rise, China's large infusion market size of more than 120 billion yuan.
The main domestic production and sales of this kind of medicine are the coren pharmaceutical, China resources two cranes, shijiazhuang four medicines and so on.
▍ injuries class orthopedics drugs
Muscle bone injuries are most common in earthquakes. Most of the injured suffered pain, swelling, bleeding or fractures, dislocations and other conditions.
In the process of emergency treatment and subsequent recovery, the injured and injured bone injuries are also urgently needed.
This kind of medicine is given priority to with proprietary Chinese medicine, common drugs are yunnan baiyao aerosol, yunnan white ointment, invigorate the circulation of analgesic capsule, yunnan baiyao band-aid, yunnan baiyao capsule, &experience spirit sprays, and yunnan baiyao powder, bone seven mile slice, &experience bone piece, etc.
At present, in China's pharmaceutical market, the market of this kind of drug is about ten billion yuan, the main production and sales manufacturers have yunnan baiyao, jiangxi baishen changno pharmaceutical, hunan sands pharmaceutical and so on.
Of course, the treatment of the injured after the earthquake is a comprehensive treatment process, the medicine listed in the article is only a part of the main medicine, for example, after the disaster also involves the plague, insect pest and so on.
Wish the people of disaster area to come out of the haze of disaster early, to pray for disaster areas!
Attached: a file called "earthquake emergency medicine catalogue" for reference.
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